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Infectious Diseases 2023

Leclercia adecarboxylata: what é, risk factors and how é the treatment

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Leclercia adecarboxylata: what é, risk factors and how é the treatment
Leclercia adecarboxylata: what é, risk factors and how é the treatment

Leclercia adecarboxylata is a bacterium that is part of the human microbiota, but can also be found in different environments, such as water, food and animals. Despite not being closely associated with diseases, some cases of Leclercia adecarboxylata have been reported in hospitals, especially in newborns admitted to the Neonatal Intensive Care Unit, due to parenteral nutrition, which can be isolated from the blood.

Leclercia adecarboxylata infection is more frequent in immunocompromised patients, which are those who have alterations in the immune system, however there are already cases of isolation of this bacterium in people who do not have any compromised immune system.

Risk factors for Leclercia adecarboxylata infection

Leclercia adecarboxylata infection is more common in people who have a weakened immune system, such as newborns or people who are hospitalized for a long time, for example. In addition, there is a greater risk of infection in people who are undergoing parenteral nutrition, use a urinary catheter, have central venous access, or are under mechanical ventilation.

In people with an efficient immune system, Leclercia adecarboxylata is usually identified together with other microorganisms, not receiving adequate treatment. However, when the immune system is weakened, it is more common for the bacteria to be identified alone in the blood, and proper treatment is essential. Understand how the diagnosis of blood infection is made.

How the treatment is done

Treatment for Leclercia adecarboxylata infection is simple, as this bacterium has shown considerable sensitivity to antibiotics. Therefore, according to the person's clinical condition and degree of compromise of the immune system, the doctor may indicate the use of Gentamicin, Ceftazidime or Glycopeptides, such as Vancomycin or Teicoplanin, for example.

Although most Leclercia adecarboxylata isolates show sensitivity to antibiotics, strains resistant to beta-lactam antibiotics are already being verified, since they are capable of producing enzymes that prevent the action of these antibiotics, which can make it difficult treatment in some situations.

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