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Medicines that delay puberty are substances that influence the functioning of the pituitary gland, preventing the release of LH and FSH, two very important hormones for the sexual development of children.
Most of the time, these drugs are used in cases of precocious puberty, to delay the process and allow the child to develop at a similar rate to children of their age.
In addition, these medications can also be used in cases of gender dysphoria, in which the child is not happy with the gender they were born, giving them more time to explore their gender before making a drastic decision. and definitive as the change of sex.
What are the most used medications
Some of the remedies that can be indicated to delay puberty are:
Leuprolide, also known as leuprorelin, is a synthetic hormone that works by decreasing the body's production of gonadotropin hormone, blocking the function of the ovaries and testes.
This medication is administered as an injection once a month, and the dose administered must be proportional to the child's weight.
Triptorelin is a synthetic hormone, with a leuprolide-like action, which must also be administered monthly.
Histrelin also works by inhibiting the body's production of the hormone gonadotropin, but is given as an implant placed under the skin for up to 12 months.
When these drugs are stopped, hormone production returns to normal and the puberty process starts quickly.
Know how to identify the symptoms of precocious puberty and see what causes are at its origin.
How medicines work
By inhibiting the gonadotropin hormone in the body, these drugs prevent the pituitary gland from producing two hormones, known as LH and FSH, which are responsible for stimulating the testes to produce testosterone in boys and the ovaries in girls producing estrogens:
- Testosterone: is the main male sex hormone, which is produced from approximately 11 years of age, and which has the role of causing hair growth, penis development and voice changes;
- Estrogen: it is known as the female hormone that begins to be produced in greater quantities around the age of 10, to stimulate breast growth, distribute fat accumulation, to create a more feminine body shape, and start the menstrual cycle.
Thus, by decreasing the amount of these sex hormones in the body, these drugs are able to delay all the typical changes of puberty, preventing the process from happening.
Possible side effects
By affecting the production of hormones, this type of medication can have some side effects in the body such as causing sudden changes in mood, joint pain, feeling short of breath, dizziness, headache, weakness and generalized pain.