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General Practice 2023

Focal nodular hyperplasia: what é, causes and treatment

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Focal nodular hyperplasia: what é, causes and treatment
Focal nodular hyperplasia: what é, causes and treatment
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Focal nodular hyperplasia is a benign tumor with about 5 cm in diameter, which is located in the liver, being the second most common benign liver tumor that, although it occurs in both sexes, is more frequent in females, in women between 20 and 50 years of age.

Generally, focal nodular hyperplasia is asymptomatic and does not require treatment, however, one should go to the doctor regularly in order to monitor its evolution. In most cases, lesions remain stable in number and size and disease progression is rarely seen.

Possible causes

Focal nodular hyperplasia can result from an increase in the number of cells in response to an increase in blood flow in an arterial malformation.

Furthermore, it is thought that the use of oral contraceptives may also be associated with this disease.

What are the signs and symptoms

Focal nodular hyperplasia is usually about 5 cm in diameter, and may, although rarely, reach more than 15 cm in diameter.

Usually, this tumor is asymptomatic, being, in most cases, found accidentally in imaging exams. Although it is very rare, it can occasionally cause acute symptoms due to bleeding.

How the treatment is done

In asymptomatic people, with typical characteristics demonstrated in imaging exams, treatment is not necessary.

Since focal nodular hyperplasia is a benign tumor without a malignant potential, surgical removal should only be performed in situations where there is doubt in the diagnosis, in evolving lesions or in people who present any symptoms.

Furthermore, in women who use contraceptives, interruption of oral contraceptive use is recommended, since contraceptives may be associated with tumor growth.

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