General Practice 2022

Memantine hydrochloride: what it is for, how to use it and side effects

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Memantine hydrochloride: what it is for, how to use it and side effects
Memantine hydrochloride: what it is for, how to use it and side effects
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Memantine hydrochloride is an oral medication used to improve memory function in people with Alzheimer's.

This medication can be found in pharmacies under the name of Ebixa.

What is it for

Memantine hydrochloride is indicated for the treatment of severe and moderate cases of Alzheimer's.

How to use

The most common dose is 10 to 20 mg per day. Usually the doctor indicates:

Start with 5mg - 1x daily, then move to 5mg twice daily, then 5mg in the morning and 10mg in the afternoon, finally 10mg twice daily, which is the target dose. For a safe progression, a minimum interval of 1 week must be respected between dose increases

This medication should not be used in children and adolescents.

Possible Side Effects

The most common side effects are: mental confusion, dizziness, headache, drowsiness, fatigue, cough, difficulty breathing, constipation, vomiting, increased pressure, back pain.

Less common reactions include heart failure, tiredness, fungal infections, confusion, hallucinations, vomiting, changes in gait and venous blood clotting such as thrombosis and thromboembolism.

When not to use

Pregnancy risk B, breastfeeding, severe kidney damage. It is also not recommended in case of allergy to memantine hydrochloride or any other component of the formula.

The use of this medication should not be used when taking the following medications: amantadine, ketamine and dextromethorphan.

During the use of this medicine, it is not recommended to consume alcoholic beverages.

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