General Practice 2022

Nistatin (mycostatin): what is it for and how to use it

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Nistatin (mycostatin): what is it for and how to use it
Nistatin (mycostatin): what is it for and how to use it
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Nystatin is an antifungal remedy that acts by inhibiting the growth of the fungus Candida albicans that can cause infections of the skin or mucous membranes such as candidiasis or moniliasis, also known as thrush in babies and children, or mycoses between the fingers, for example..

This drug is available in pharmacies and drugstores in the form of an oral suspension, vaginal cream or dermatological ointment, under the trade name Micostatin, or as a generic under the name nystatin, and must be used with medical indication. In addition, nystatin can be found in the form of vaginal eggs, containing another associated substance, metronidazole, being indicated for the treatment of candidiasis or vaginal infections caused by Trichomonas or Gardnerella vaginalis, found under the trade name Gynotran.

What is it for

Nystatin is indicated for the treatment of infections caused by the fungus Candida albicans, such as candidiasis of the vagina or mouth, esophagus or intestines, thrush or diaper rash in babies or children, or ringworm between the fingers, armpit or on the breasts.

How to use

How to use nystatin varies by presentation and includes:

1. Nystatin oral suspension

Nystatin oral suspension should be used after brushing teeth, cleaning the mouth of babies and children, or cleaning dentures.

To measure the right amount of dose, use the dispenser that comes with the nystatin oral suspension bottle.

The dose of Nystatin Oral Suspension varies by age and includes:

  • Premature babies or low birth weight children: the dose is 1 mL of oral suspension, 4 times a day, that is, 1 dose every 6 hours;
  • Breastfeeding babies: The recommended dose is 1 to 2 mL of the oral suspension, 4 times a day, ie 1 dose every 6 hours. Breastfeeding the baby should be avoided for at least 5 minutes after the nystatin dose;
  • Children and adults: the dose is 1 to 6 mL of oral suspension, 4 times a day.

The oral suspension of nystatin should be swished and kept in the mouth for as long as possible before swallowing, and in babies and infants, half the dose should be applied to each side of the mouth.

It is important to shake the bottle of nystatin suspension, before use, to mix its components and have the expected effect of the treatment.

After the symptoms disappear, the application should be continued for another 2 days to avoid recurrence.

2. Nystatin vaginal cream

Nystatin Vaginal Cream should be used once a day, preferably at night, for 14 days and should be applied deeply into the vaginal canal using the applicator provided in the package.If you forget to take a dose at night, take it the next morning and then continue the treatment at the correct time. If the symptoms do not disappear within 14 days, you should return to the doctor.

To use nystatin vaginal cream, wash your hands well before and after use. Pull the applicator plunger all the way out, remove the cream cap and fit the applicator onto the cream tube nozzle, screwing it in so it stays tight. Squeeze the cream tube to fill the applicator and, when full, unscrew the tube and cap the cream. Lie down with your legs bent and slightly spread and carefully insert the applicator filled with cream into the vaginal canal, pushing the plunger all the way in. Remove the applicator and discard it.

The application of nystatin vaginal cream should not be interrupted during menstruation and the use of tampons, vaginal douches or spermicides should be avoided during treatment.

3. Nystatin Dermatological Ointment

Nystatin dermatological ointment is usually associated with zinc oxide, which works as a skin protector.

Recommended doses of nystatin dermatological ointment include:

  • Diaper rash in babies and children: use with every diaper change if baby has severe diaper rash. To prevent diaper rash, it can be applied twice a day. It is important that the baby's skin is clean and dry before application;
  • Skin irritation or ringworm between the fingers, armpit or breasts: apply the dermatological cream, 2 times a day, in the affected regions.

The treatment time with nystatin dermatological ointment may vary, and should be guided by the doctor.

4. Nystatin vaginal eggs

Nystatin vaginal eggs contain another drug in their composition, metronidazole, which is an antimicrobial indicated for the treatment of candidiasis or vaginal infections caused by Trichomonas or Gardnerella vaginalis.

These eggs are solid preparations, similar to suppositories, but which are indicated for vaginal use, as they melt at 37ยบ in the vagina or in the vaginal secretion.

Before using the egg, wash your hands well, as the application can be done using your finger or with an applicator provided in the package. The ideal position to apply the egg in the vagina is lying on your back with your legs bent, a little apart from each other. Then, insert the egg deeply into the vagina, once a day, preferably at night, for 7 days, as directed by your doctor. After application, wash your hands thoroughly with soap and water.

The application of the egg should not be interrupted during menstruation and the use of tampons, vaginal douches or spermicides should be avoided during treatment. In addition, it is important to avoid prolonged contact of the egg with your hands, as it can dissolve and make application difficult.

Possible side effects

The most common side effects of nystatin vary with the form of use, and in the case of oral suspension, vomiting, nausea, diarrhea or abdominal pain may occur.

In the case of vaginal eggs, vaginal cream or dermatological ointment may cause itching, local irritation or a burning sensation on the skin.

It is recommended to discontinue treatment and seek medical help if the person has irritation or allergy to this medication.

Who should not use

Nystatin should not be used during pregnancy or breastfeeding or by people allergic to nystatin.

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