General Practice 2022

Femproporex (Desobesi-M): what it is for, how to take it and side effects

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Femproporex (Desobesi-M): what it is for, how to take it and side effects
Femproporex (Desobesi-M): what it is for, how to take it and side effects

Femproporex is the active substance of Desobesi-M, indicated for the treatment of obesity, which acts directly on the center that regulates appetite in the brain, decreasing hunger, in addition to causing a change in taste and smell, which leads to a decrease in food intake, facilitating weight loss.

This drug was withdrawn from the market in 2011 by ANVISA, due to the lack of scientific studies proving its effectiveness in weight reduction and the risk of developing serious side effects, such as heart or psychiatric problems.

For this reason, Desobesi-M is no longer produced by the Aché laboratory, and there is no forecast of its being available for sale again.

What is it for

Femproporex is indicated for the treatment of obesity in adults due to its action on the brain that causes a reduction in appetite and a decrease in the sense of taste and odor, which leads the person to decrease food intake, leading to loss of weight.

How to take it

The recommended dose of fenproporex is 1 capsule of 25 mg per day, taken orally, in the morning, around 10 am. However, the schedule and dose can be adapted by the doctor according to each case.

Possible side effects

The most common side effects that may occur during treatment with fenproporex are vertigo, tremor, irritability, agitation, excessive weakness, tension, insomnia, mental confusion, anxiety, headache, dry mouth or metallic taste in the mouth.

Furthermore, chills, pallor or flushing of the cheeks, palpitation, cardiac arrhythmia, chest pain, hypertension or hypotension, circulatory collapse, nausea, vomiting, diarrhea, abdominal cramps, and altered sexual desire may also occur.Prolonged use may cause addiction or tolerance.

Who should not take it

Femproporex should not be used by children, pregnant or breastfeeding women, or by people who are allergic to any of the components of the formula, or who have psychiatric problems, epilepsy, chronic alcoholism, cardiovascular problems such as high blood pressure, or hypothyroidism, glaucoma, extrapyramidal changes, or with a history of drug abuse.

Furthermore, the use of fenproporex in patients with mild hypertension, kidney disease, unstable personality or diabetes should only be done under medical supervision.

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