General Practice 2022

Contrave: what is it for and how to take it

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Contrave: what is it for and how to take it
Contrave: what is it for and how to take it

Contrave is a remedy indicated to aid weight loss in people who suffer from obesity or overweight, as it contains two substances in its composition, bupropion and n altrexone, which act on the brain by reducing and controlling appetite, in addition to desire. intense for food, which leads to a decrease in food consumption.

And this remedy allows you to lose up to 10% of your weight in 12 months when combined with a he althy diet and regular exercise. In addition, Contrave allows you to reduce your waist circumference, preventing diabetes or heart disease, for example.

Contrave is approved by ANVISA and can be found in pharmacies or drugstores in the form of capsules, containing 90 mg of bupropion hydrochloride and 8 mg of n altrexone hydrochloride, sold only with a doctor's prescription and prescription retention by the pharmacy.

What is it for

Contrave is indicated for the treatment of obesity in adults with a BMI greater than 30 kg/m², or in overweight adults whose BMI is greater than 27 kg/m2, and there are other related diseases such as diabetes, high cholesterol or high blood pressure. See how to calculate BMI.

This remedy should be used with medical advice and only to complement the treatment of obesity or overweight, which should also include a low-calorie diet and regular physical exercise.

It is important to emphasize that Contrave does not treat diabetes, high cholesterol or high blood pressure, but it helps with weight loss, which favors a better control of these diseases.

How to take it

The normally recommended dose of Contrave is 1 capsule in the morning and one in the evening, or as directed by your doctor.

Contrave should be taken orally with a glass of water, without breaking, opening or chewing the capsule, and should not be taken with high-fat meals.

If you miss a dose, take it as soon as you remember, and it is recommended to skip the missed dose if it is close to the next dose. It is not recommended to take two capsules at once to make up for a missed dose.

Possible side effects

The most common side effects that may occur during treatment with Contrave are dry mouth, headache, dizziness, constipation or diarrhea, nausea, vomiting, insomnia, irritability, depression, anxiety, restlessness, pain muscle or joints.

These side effects are more common in the first few weeks of treatment and usually tend to subside over time. Medical help should be sought immediately if symptoms such as increased heart rate, severe headache, blurred vision, ringing in the ears, anxiety or seizure occur.

In addition, Contrave can cause severe allergic reactions that also require immediate medical attention.Therefore, treatment should be discontinued and the nearest emergency department should be sought when symptoms of severe allergy such as difficulty breathing, feeling of a closed throat, swelling in the mouth, tongue or face, itching or hives, fever or formation of sores or lumps on the skin. Know how to identify the symptoms of a severe allergic reaction.

Who should not use

Contrave should not be used by children or adolescents under the age of 18, pregnant or nursing women, or by anyone who is allergic to bupropion, n altrexone or any other component of the formula.

Also, Contrave should not be in cases of:

  • Heart disease, high blood pressure, heart attack or stroke;
  • Depression or bipolar disorder;
  • Suicidal thoughts;
  • History of seizure disorder;
  • Tumor or infection in the brain or spinal cord;
  • Hypoglycemia;
  • Low blood sodium levels;
  • Hepatic or kidney failure;
  • Treatment of drug addiction or alcohol abuse;
  • Dependence on opioid medication or on opioid treatment.

Contrave should also not be used by people using monoamine oxidase inhibitor (MAOI) drugs, such as isocarboxazid, phenelzine or tranylcypromine, for example, and should wait at least 14 days after the end of treatment with the drugs. monoamine oxidase inhibitors to initiate treatment with Contrave.

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