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Frosemide is a drug indicated for the treatment of mild to moderate hypertension and for the treatment of swelling due to disorders of the heart, liver, kidneys or burns, due to its diuretic and antihypertensive effect.
This medication is available in pharmacies in generic or under the trade names Lasix or Neosemid, in pills or injection, and can be purchased for a price of around 5 to 14 reais, depending on whether the person chooses the brand or generic, requiring the presentation of a medical prescription.
What is it for
Furosemide is indicated for the treatment of mild to moderate high blood pressure, swelling of the body due to heart, liver or kidney problems or due to burns.
How to use
The way to use furosemide should be guided by the doctor, and usually varies between 20 to 80 mg a day, at the beginning of the treatment, as needed. The maintenance dose is 20 to 40 mg daily.
In children, the recommended dosage is normally 2 mg/kg body weight, up to a maximum of 40 mg per day.
Injectable furosemide should only be used in a hospital setting, and should be administered by a he althcare professional.
What is the action mechanism
Frosemide is a loop diuretic that produces a potent diuretic effect with a rapid onset of action and short duration. The diuretic action of furosemide results from the inhibition of sodium chloride reabsorption in the loop of Henle, leading to increased sodium excretion and, consequently, a greater volume of urinary excretion.
Learn about other mechanisms of action of different types of diuretics.
Possible side effects
Some of the most common side effects that may occur during treatment with furosemide are electrolyte disturbances, dehydration and hypovolemia, especially in elderly patients, increase in blood creatinine and triglyceride levels, hyponatremia, reduction in potassium levels and chloride in the blood, increased levels of cholesterol and uric acid in the blood, attacks of gout and increased urinary volume.
Who should not use
Furosemide is contraindicated in people with hypersensitivity to the components of the formula.
In addition, it should not be used in lactating women, in patients with kidney failure with total cessation of urinary elimination, pre-coma and coma due to liver encephalopathy, in patients with reduced potassium levels and sodium in the blood, with dehydration or decreased circulating blood.