General Practice 2022

Remédios that can cause miscarriage

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Remédios that can cause miscarriage
Remédios that can cause miscarriage

The use of medication during pregnancy should always be done only with the guidance of an obstetrician, as most drugs have the potential to cause problems during pregnancy and even result in a miscarriage.

Drugs such as thalidomide, atorvastatin or isotretinoin are completely contraindicated during pregnancy because they can cause damage or malformations to the fetus that can be born with severe deficiencies or cause miscarriage.

However, when abortion is legally permitted, as in cases of rape or when pregnancy puts the woman's life at risk, for example, misoprostol is the drug most used by doctors in hospitals. This medication cannot be sold in pharmacies, being restricted only to hospitals.

Medicines that should not be used in pregnancy

Remedies that can cause miscarriage or fetal harm and malformations and therefore cannot be used during pregnancy are:


What is it for

Misoprostol It is used in the hospital to terminate a pregnancy in pregnancies that are close to 40 weeks or to induce labor before 30 weeks when the fetus is dead, in case of a legal abortion.
Misoprostol + diclofenac It is indicated for the treatment of pain and swelling in the joints caused by rheumatoid arthritis or osteoarthritis.
Mifepristone It is used in the hospital to terminate a pregnancy in case of a legal abortion.
Isotretinoin It is indicated for the treatment of severe acne.
Atorvastatin It is used to treat high cholesterol.
Radioactive Iodine It is used to treat thyroid cancer and as a contrast in scintigraphy tests to detect thyroid cancer cells.
Thalidomide It is used to treat leprosy, lupus erythematosus, multiple myeloma or graft-versus-host disease.

Other drugs that are potentially abortifacient and that can only be used under medical indication when their benefits outweigh the risk of abortion are amitriptyline, phenobarbital, valproic acid, cortisone, methadone, doxorubicin, enalapril and others that have risk D or X indicated in this way in the package insert of such drugs.See the symptoms that may indicate a miscarriage.

In addition, whenever possible, the use of teas during pregnancy should be avoided, especially when used without medical advice, as there are no studies that confirm their safety during pregnancy. However, some teas such as licorice, borage or parsley are totally contraindicated because there is scientific evidence that they can cause abortion or malformations in the fetus. Check out a more complete list of teas that should not be used during pregnancy.

When abortion is allowed

Abortion allowed in Brazil must be performed by the doctor inside a Hospital, being legal only when one of the following conditions is present:

  • Pregnancy due to rape;
  • Pregnancy that puts the mother's life at risk, with abortion being the only way to save the pregnant woman's life;
  • When the fetus has a fetal malformation incompatible with life after birth, such as anencephaly.

Thus, for a woman to be able to resort to abortion in any of these situations, she must authorize the abortion or, in the case of children under 18, the person responsible for the child must authorize the procedure. In the case of women who for some reason are unconscious or unable to authorize the procedure, abortion can be performed by the doctor if the woman's life is at risk.

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