General Practice 2022

Pregabalin: what é, what it is for and how to use it

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Pregabalin: what é, what it is for and how to use it
Pregabalin: what é, what it is for and how to use it
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Pregabalin is a drug that acts on the nervous system, regulating the activities of nerve cells, being indicated for the treatment of epilepsy and neuropathic pain, caused by the malfunction of the nerves. In addition, it is also used in the treatment of generalized anxiety disorder and in the management of pain caused by fibromyalgia in adults.

This drug can be purchased in pharmacies or drugstores in the form of 75 mg and 150 mg capsules, with the trade name Lyrica, in the generic form with the name pregabalin, or with the similar names Prebictal, Insit or Prefiss, and is sold only by prescription and withholding by the pharmacy.

What is it for

Pregabalin is indicated for the treatment of peripheral and central neuropathic pain, partial seizures of epilepsy, generalized anxiety disorder and the management of fibromyalgia in adults.

How to use

Pregabalin should be taken orally with a glass of water, before or after food, at the dose, time and for the period of time established by the doctor. However, if you forget to take a dose on time, take it as soon as you remember, but skip the missed dose if it is almost time for your next dose. Do not double the dose to make up for the missed dose.

Pregabalin use by adults varies according to the indication and includes:

1. Neuropathic pain

The recommended starting dose is 75 mg twice daily. Depending on the individual response and tolerability of the person undergoing treatment, the dose may be increased by the doctor to 150 mg twice daily after an interval of 3 to 7 days and, if necessary, up to a maximum dose of 300 mg, 2 times a day, after another week.

Learn the symptoms and causes of neuropathic pain.

2. Epilepsy

The recommended starting dose is 75 mg twice daily. Depending on the person's response and tolerability, the dose may be increased to 150 mg twice daily after 1 week of treatment. If necessary, after one week, the dose can be increased to up to 300 mg, twice a day, as directed by a physician.

See how to identify the symptoms of epilepsy.

3. Generalized Anxiety Disorder

The recommended effective starting dose is 75 mg twice daily. Depending on the person's response and tolerability, the dose may be increased by the doctor to 300 mg daily after 1 week, and after a further week it may be increased to 450 mg daily, up to a maximum dose of 600 mg daily, which can be reached after another 1 week.

Learn what Generalized Anxiety Disorder is.

4. Fibromyalgia

Dose should start at 75 mg twice daily and may be increased to 150 mg twice daily within one week, depending on individual efficacy and tolerability. For people who have not experienced sufficient benefit from a dose of 300 mg daily, the dose may be increased to 225 mg twice daily as directed by a physician.

Know the symptoms of fibromyalgia.

Possible side effects

The most common side effects that may occur with the use of this medication are nasopharyngitis, increased appetite, euphoric mood, confusion, irritability, depression, disorientation, insomnia, decreased sexual appetite, abnormal coordination, dizziness, drowsiness, tremors, difficulty articulating words, memory loss, changes in balance, disturbances in attention, sedation, lethargy, tingling or changes in sensation in the limbs, changes in vision, vertigo, vomiting, constipation, excess intestinal gas, mouth dryness, muscle pain, walking difficulties, fatigue, weight gain and general swelling.

Does pregabalin make you fat?

One of the common side effects of pregabalin is weight gain, so it is likely that some people gain weight during treatment with this drug. However, not all people gain weight on pregabalin, studies show that only 1 to 10% of people experience weight gain.

Who should not use

Pregabalin should not be used by people allergic to any of the compounds in the formula. In addition, this medication may only be used during pregnancy and breastfeeding under the guidance of a physician.

Some diabetic patients who are being treated with pregabalin and who gain weight may need to adjust their diabetes medication.

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